Sigma A4262   Actinomycin D   放线菌素D

产品说明:

Molecular Formula:  C₆₂H₈₆N₁₂O₁₆

Molecular Weight:   1255.42

CAS Number 50-76-0

Descriptions:

Biochem/physiol Actions

An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes.

Properties

biological source ………………………………………from Streptomyces sp.

Assay…………………………………………95% (HPLC)

color ………………………………………………………red, powder

solubility …………………………………………………ethanol, DMSO: soluble

storage temp…………………………………………… 2-8°C