Sigma S0130      链脲佐菌素 Streptozocin （STZ)

产品说明：

Synonym： N-(Methylnitrosocarbamoyl)-α-D-glucosamine

                     Streptozotocin

Molecular Formula：C₈H₁₅N₃O₇

Molecular Weight：265.22

CAS Number： 18883-66-4

Descriptions:

Other Notes……………..……Mixed anomers

Biochem/physiol Actions……An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets; induces death of insulin-secreting cells, producing an animal model of diabetes. Potent DNA methylating agent that induces chromosomal breakage.1 Cytotoxic to neuroendocrine tumor cell lines that express the GLUT2 glucose transporter.

Properties:

assay ……………………≥75% as α-anomer

         ……………………≥98% (HPLC)

form ……………………………powder

color……………………………white to off-white

mp ……………………………121 °C (dec.)(lit.)

storage temp…………………−20°C